Clinical Research Initiatives The Multi Organ Transplant Program strongly encourages clinical research designed to evaluate and advance the science of transplantation, and the care of transplant patients. To date a number of clinical studies have been conducted examining quality of life issues and predictive clinical outcomes.

The program promotes research efforts from all health disciplines and welcomes opportunities to enhance transplant practice through clinical investigations.

Clinical Trials Department

Currently the Multi Organ Transplant Program is involved in over 25 clinical trials involving over 240 transplant recipients. Our unique Clinical Trials department structure enables efficient and effective management of a multitude of studies. The Clinical Trials department manages local, national and international studies with high patient enrollment and thorough protocol compliance, while maintaining a strong commitment to high quality patient care.

Clinical trials opportunities are available for transplant patients from all organ groups. Studies involve both newly transplanted patients as well as patients who have been transplanted several years ago. The Clinical Trials department ensures that every eligible patient is presented with the opportunity to consider participating in the most current trials available.

The majority of these clinical trials consist of immunosuppressive drugs. Several of these drugs are currently on the market, however current studies focus on evaluation of the medications for a wide range of indications, at varying doses. There are also new immunosuppressive drugs being tested, some of which are in early stages of development.

In addition to immunosuppressive drugs, the MOT unit is undertaking trials examining factors relating to Hepatitis B, Hepatitis C, and cytomegalovirus (CMV). New drugs are being explored in all these areas and promise new insight into our understanding of these viruses, their ability to re-infect the host patient, and their effects on immunosuppressed patients. Several of the trials conducted at this centre have been presented at international congresses and transplant meetings. Recent publications in several professional journals highlight program achievements in research.